Ezimbonini zemithi nezokunakekelwa kwezempilo, amaphilisi angenalutho asebenza njengezihlanganisi ezibalulekile zemithi, futhi ukusebenza kwawo kuthinta ngokuqondile ukuzinza nokuba khona kwe-bioavailability yamalungiselelo. Nakuba amaphilisi e-gelatin kudala ebusa imakethe, ukulinganiselwa kwawo okungokwemvelo kukhawulele ukusetshenziswa kwawo emikhakheni ethile{1}}ephezulu. Eminyakeni yakamuva, amaphilisi e-pululan, njengesitshalo esisafufusa{3}inketho ye-capsule esekelwe, kancane kancane abe yinketho ekhethwayo{4}}yamalungiselelo aphezulu emithi nokudla okusebenzayo ngenxa yezakhiwo zawo ezihlukile ze-physicochemical. Okulandelayo yizinzuzo eziyinhloko zama-capsules we-pululan.
Okokuqala futhi okubaluleke kakhulu, ukusebenza kwesithiyo esiphezulu kuyinzuzo evelele kakhulu yama-capsules e-pululan. I-Pullulan iyi-polysaccharide eqondile ukwakheka kwayo kwe-molecular helical kubangela ifilimu eliminyene kakhulu{1}}elinamandla okwenza ifilimu. Lesi sici sinikeza ama-capsules e-pululan ane-oksijeni ephansi kakhulu kanye namazinga okudlulisa umswakama. Uma kuqhathaniswa namakhepsuli e-gelatin, avimba ngempumelelo kakhulu ukungena komoyampilo wangaphandle nomhwamuko wamanzi, anikeze cishe indawo engenalutho{4}efana nezinzile kokuqukethwe. Lokhu kubalulekile ekuqinisekiseni umsebenzi namandla okuqukethwe okungenwa kalula umswakama kanye ne-oxidation, njengama-probiotics, okukhishwe kwemithi yendabuko yamaShayina, namavithamini.
Okwesibili, amaphilisi e-pululan anokuqina okuhle ngokomzimba, ayixazulula kahle inkinga-yokuxhumanisa. Amaphilisi e-gelatin avamile athambekele ekunqandeni{2}}ukusabela okuxhumanisayo lapho egcinwe{3}}emazingeni okushisa aphezulu,{4}}ezindaweni ezinomswakama ophezulu noma lapho echayeke kuma-aldehyde. Lokhu kungabangela ukuthi igobolondo le-capsule lincibilike kancane kancane noma liholele ekuhlukaneni okulibaziseke, ngaleyo ndlela kuthinte ukumuncwa kwezidakamizwa emzimbeni. Ngokuphambene, ama-capsules e-pululan azinzile kumakhemikhali; awasabeli nge-aldehyde{7}equkethe izidakamizwa futhi awakwazi ukuhlangana-nokuxhumana. Lokhu kuqinisekisa ukuthi umuthi ukhishwa ngokushesha emzimbeni njengoba kulindelekile, okuqinisekisa ukusebenza ngempumelelo kokwelapha.
Ngaphezu kwalokho, ama-capsules e-pululan abonisa ukuguquguquka okubanzi kwesitoreji. Amakhepsuli eGelatin ajwayele ukulahlekelwa amanzi futhi abe nzima ezindaweni{1}}ezinomswakama omncane, kuyilapho ethambile noma enamathelana{2}}ezindaweni ezinomswakama ophezulu, ngaleyo ndlela kufuna izimo eziqinile zokulondoloza. Amaphilisi e-Pullulan, nokho, agcina ukuqina okuhle kumazinga okushisa ahlukene kanye nomswakama. Abathambekele ekubeni brittleness noma ukuwohloka, ehlisa kakhulu ukulahlekelwa ngesikhathi sokuhamba, ezokuthutha, kanye nokugcinwa kwempahla.
Ekugcineni, banikeza ukuphepha okuphezulu futhi bahambisane nemikhuba yemvelo. Amaphilisi ama-pullulan asuselwa ekuvubeleni kwe-microbial, okuwenza angabi{1}}aphuma ezilwaneni. Lokhu kuqeda ngokuphelele ubungozi bokudlulisa{3}izifo ezithwalwa yizilwane (ezifana ne-BSE) futhi ngesikhathi esisodwa kuhlangabezana nezidingo zabantu abadla imifino kanye nabantu abanemikhawulo ethile yezenkolo yokudla. Ukwengeza, izinto zokusetshenziswa ziyakwazi ukubola ngokwemvelo, okwenza umkhiqizo ube nemvelo-kakhudlwana.
Ngokufigqiwe,ama-capsules we-pululankhombisa izinzuzo ezingenakuthathelwa indawo ngamakhono azo amahle kakhulu okuvimbela umoya-mpilo kanye nomswakama, ukuzinza komzimba okuphakeme, ukuguquguquka okuhle kwesitoreji, kanye nephrofayili ephezulu yokuphepha. Ngokuthuthuka okuqhubekayo kobuchwepheshe bezemithi, amaphilisi e-pululan akulungele ukudlala indima ebaluleke kakhulu esikhathini esizayo{1}}imakethe yemithi ephezulu. Uma kukhona okufunwayo kumaphilisi angenalutho, wamukelekile ukuthintana ne-KornnacCaps.
