Usayizi 0 Enteric Coated Capsules

I-Enteric Coated Gelatin Capsules iwuhlobo lwe-capsule engenalutho futhi eqinile eyenziwe nge-gelatin yamakhepsuli anezinsiza ezingeziwe ezisizayo nezinto ezifanele ze-enteric. Ku-hydrochloric acid pH 1.2 medium, ayizange ihlakazeke futhi ikhishwe phakathi namahora angu-2. Isampula yadluliselwa ku-pH 6.8 phosphate buffer medium futhi yahlakazeka ngokuphelele phakathi nehora elingu-1.

▶Ifakwe Imigqa Yokukhiqiza ye-PTS, enesistimu yesol ehlakaniphile-yejeli, okokusebenza kokushintsha kwe-viscosity okuzenzakalelayo, Isistimu Yemoto Eqondiswayo, ipayipi lokukhipha i-capsule, elinokulawula{1}}okuzenzakalelayo nokusebenza ngokugcwele, ubuchwepheshe benqubo eyinhloko ukuze kuqinisekiswe, kulandeleke izinqubo, ngekhwalithi ephezulu;

 

▶ Ngemisebenzi yokulawula ezenzakalelayo ngokugcwele, inqubo eqinile yokuhlanza endlini kanye nokuqapha ikhwalithi, nezimo zenqubo yezinga lokushisa elingashintshi kanye nomswakamo, i-ethylene oxide{0}inzalo yamahhala ifinyelelwa;

 

▶Amaphilisi anama-enteric ahlanganiswe yinkampani yethu athobela izindinganiso ze-Chinese Pharmacopoeia futhi anezinto ezilandelayo zokulawula ikhwalithi;

Ngaphambi kokuthi amaphilisi ethu e-gelatin-ahlanganiswe angenalutho e-enteric{1}}ahlanganiswe angenalutho e-HPMC apakishwe futhi afakwe emakethe, kufanele ahlangabezane nezindinganiso zekhwalithi;

 

▶Kumakhepsuli e-gelatin-ahlanganiswe angenalutho e-enteric, kufanele ahlolwe{1}}nokuqina kwesikhathi eside ukuze ahlole izakhiwo zawo, ukuhlonza, ukuqina, isikhathi sokuhlakazeka, ama-sulfite, ukulahleka kokoma, izinsalela zokuvutha, izinsimbi ezisindayo nezinye izinkomba zokuzinza;

 

▶Kumakhepsuli e-HPMC-ahlanganiswe angenalutho e-enteric, kufanele ahlolwe ngokushesha ukuze ahlole izakhiwo zawo, ukuhlonza, ukuqina kwawo, ukuqina kwawo, isikhathi sokuhlakazeka, ukulahlekelwa okomile, izinsalela zokuvutha, izinsimbi ezisindayo, usawoti we-arsenic nezinye izinkomba zokuzinza.

• Sithobelana ngokuqinile namazinga e-GMP azuzayo ekhemisi futhi sizuze Isitifiketi Se-ISO 9001 Yohlelo Lokuphathwa Kwekhwalithi. Ukusekela ukukhiqizwa kwesayensi, okujwayelekile, kanye{2}}nekhwalithi ephezulu kuwumthwalo wethu oyinhloko.

 

• Ukuze kulethwe{0}}amaphilisi angenalutho ekhwalithi ephezulu, aphephile, futhi anempilo, sonke isigaba sokukhiqiza silandela izinqubo zokusebenza eziqinile nezilawuli zekhwalithi eziqinile.

Lawula

1. Impahla eluhlaza

2. Hlola impahla eluhlaza

3. Ukuncibilika

4. Ukukhiqizwa kwe-Capsule

5. Ukuphrinta(kuyacelwa)

6. Ukuhlolwa ngomshini

7. Ukubala nokupakisha

8. Ukuhlolwa komkhiqizo elebhu

Imikhiqizo yethu ithobela izindinganiso ze-Chinese Pharmacopoeia futhi ithole izitifiketi eziningi zamazwe ngamazwe, okuhlanganisa i-HALAL, i-Kosher, i-FDA, i-ISO 9001, ne-ISO 22000.

Ukupakisha

● PE bag+Aluminium foil bag+Six surface foam board+5 ply corrugated Carton

● Usayizi webhokisi: 60x73x40cm; umthamo: 0.18 cubic metres; isisindo esiphelele singaba ngu-15kgs ibhokisi ngalinye.

● Isitsha sesiqandisi esingu-20: amabhokisi angama-140 ama-capsules angenalutho;

● 40' Isitsha Sefriji: Amabhokisi angama-345 amaphilisi angenalutho.

 

Isitoreji

● Ama-capsules angenalutho kufanele agcinwe ekamelweni ngezinga lokushisa eliphakathi kuka-10-25℃kanye nomswakama ohlobene no-35-65%;

● Ibhokisi le-capsule kufanele ligcinwe kude nezindonga kanye nebanga elithile ukusuka phansi ukuze kugwenywe umswakama;

● Gwema ukukhanya kwelanga okuqondile, gwema ukukhiqiza ukushisa nemithombo yamanzi;

 

Itholakalela ukwenziwa ngokwezifiso ngokwezidingo zekhasimende.

Izinzuzo Eziyinhloko Ze-Enteric-Ama-Capsules Ahlanganisiwe
1.Ukuvikela Izidakamizwa Ekubhujisweni I-Gastric Acid
Ezinye izidakamizwa zijwayele ukungasebenzi noma ukuwohloka endaweni ene-asidi yesisu, okuthinta ukusebenza kahle kwazo. Idizayini yama-enteric{1}}amakhepsuli ane-coated iqinisekisa ukuthi imishanguzo ayidedelwa esiswini, ngaleyo ndlela ivimbele ukuwohloka kwezingxenye zomuthi endaweni ene-acidic kanye nokuqinisekisa ukusebenza kahle kwezidakamizwa.
2.Yehlisa Ukucasuka ku-Gastric Mucosa
Eminye imithi (njenge-aspirin) inomphumela onamandla ocasulayo ku-mucosa yesisu, okungase kubangele ubuhlungu besisu, izilonda nezinye izinkinga. Ama-Enteric{1}ama-capsules ane-coated akhulula izidakamizwa emathunjini, ehlisa ukuthintana okuqondile kwezidakamizwa ne-gastric mucosa futhi ehlise izehlakalo zokungakhululeki kwesisu kanye nokusabela okungekuhle kwesisu.
3.Ukukhishwa Kwezidakamizwa Okuqondile
Ama-capsules{0}enziwe nge-Enteric angakhipha izidakamizwa kumasayithi athile emathunjini, ngaleyo ndlela enze ngcono umphumela wokwelapha wendawo wezidakamizwa. Isibonelo, lapho ukwelapha izifo zamathumbu, izidakamizwa zingasebenza ngokuqondile ezindaweni ezithintekile, zithuthukise umphumela wokwelapha.
4.Thuthukisa Ukuzinza Kwezidakamizwa
Igobolondo le-capsule-elinamekwe nge-enteric livikela umuthi ethonyeni le-gastric acid, ngaleyo ndlela andise impilo yeshalofu yomuthi futhi iqinisekise ukuthi umuthi uhlala usebenza lapho ufika emathunjini.
5.Yehlisa Umthamo Wezidakamizwa
Ngenxa yokumuncwa ngempumelelo komuthi emathunjini, kwezinye izimo, umthamo womuthi ungancishiswa, ngaleyo ndlela kuncishiswe umthwalo wezomnotho ezigulini.

Izinkambu Zokusebenza Ezicacisiwe zama-Enteric-Ama-Capsules Ahlanganisiwe

Ububanzi bokusetshenziswa kwamakhepsuli{0}}ahlanganisiwe bubanzi kakhulu futhi buhlanganisa imikhakha yezokwelapha eminingi:
1.Enkundleni Yemithi Yendabuko YamaShayina
Emalungiselweni emithi yendabuko yamaShayina, amaphilisi{0}}ahlanganisiwe avame ukusetshenziselwa ukuhlanganisa izidakamizwa ezicasulayo esiswini noma ezidinga ukumuncwa ngamathumbu. Lo mklamo wehlisa ukucasuka komuthi wendabuko waseShayina olayini lwesisu futhi uthuthukisa ukunethezeka kwemithi yesiguli.

2.Chemical Drug Field
Kweminye imishanguzo yamakhemikhali, ikakhulukazi leyo edinga ukugcina ukugxila okuthile emathunjini noma ikhululwe ngaphansi kwezimo ezithile, amaphilisi{0}}ahlanganiswe ngama-enteric angabathwali abafanelekile.

3.I-Biochemical Drug Field
Izidakamizwa ze-biochemical ngokuvamile zinezidingo eziphezulu zemvelo. Ama-capsules{1}enziwe nge-Enteric anganikeza ukuvikeleka okuzinzile, okuqinisekisa ukuthi izidakamizwa zihlala zisebenza futhi zizinzile emgudwini wamathumbu.

4.Ukwelashwa Kwezifo Ezikhethekile
Ama-capsules{0}e-enteric abambe iqhaza elikhulu ekwelapheni izifo ezithile. Isibonelo, amaphilisi e-budesonide enteric{2}}ahlanganiswe, njenge-immunomodulator ehlosiwe ye-mucosa yamathumbu, asetshenziswa kakhulu ekwelapheni i-IgA nephropathy. Ngokunciphisa ukukhiqizwa kwe-IgA ye-pathogenic, lesi sidakamizwa singenelela enqubweni yesifo emthonjeni waso, sinciphisa kakhulu i-proteinuria nokuvikela umsebenzi wezinso.

Amashadi ashisayo: Usayizi 0 we-enteric capsules, i-China usayizi 0 we-enteric coated capsule abakhiqizi, abahlinzeki, imboni